Sodium Butyrate Inhibits Cell Growth and Stimulates P21 Protein in Human Colonic Adenocarcimoma Cells Independently of P53 Status, Kobayashi, Tan & Fleming, Nutr. & Cancer 2003; 46 (2): 202-211.

BUTYRATE Sodium Butyrate Inhibits Cell Growth and Stimulates P21 Protein in Human Colonic Adenocarcimoma Cells Independently of P53 Status, Kobayashi, Tan & Fleming, Nutr. & Cancer  2003; 46 (2): 202-211. Butyrate Induces Glutathione S-Transferase in Human Colon Cells and Protects from Genetic Damage by 4-Hydroxy-2-Nonenal,  Ebert, et al.,  Nutr. & Cancer 2001; 41 (1): 156-164. Topical Butyrate for Acute Radiation Proctitis: Randomised, Cross-over Trial, Vernia, Fracasso, Casale, et al.,  Lancet  2000; 356 (9237): 1232-1235.

CHINESE MEDICINE (TCM) HERBS & ACUPUNCTURE Traditional Chinese Medicine In Cancer Symposium, Vanc. Gen. Hosp. Sept. 21, 2003 Astragalus-based Chinese Herbs and Platinum-based Chemotherapy for Advanced Non-small-cell Lung Cancer: Meta-analysis of Randomized Trials, McCulloch, See, Shu, et al., J. Clin. Oncol. 2006; 24 (3): 419-430. Traditional Chinese Medicine Astragalus Reverses Predominance of Th2 Cytokines and Their Up-stream Transcript Factors in Lung Cancer Patients, Wei, Sun, Xiao, et al., Oncol. Rep. 2003; 10 (5): 1507-1512 Shi-Quan-Da-Bu-Tang (Ten Significant Tonic Decoction), SQT. A Potent Chinese Biological Response Modifier in Cancer Immunotherapy, Potentiation and Detoxification of Anticancer Drugs, Zee-Cheng, Meth. Find. Exp. Clin. Pharmacol. 1992; 14 (9): 725-736. A Phase II Study of an Herbal Decoction That Includes Astragali Radix for Cancer-Associated Anorexia in Patients with Advanced Cancer, Lee & Lee,  Integr. Cancer Ther. 2010;  9 (1): 24-31. Immunotherapy with Chinese Medicinal Herbs. I. Immune Restoration of Local Xenogeneic Graft-versus-host Reaction in Cancer Patients by Fractionated Astragalus membranaceus in vitro, Chu, Wong & Mavligit,  J. Clin. Lab. Immunol. 1988; (3): 119-123. Clinical Study on Effect of Astragalus in Efficacy Enhancing and Toxicity Reducing of Chemotherapy in Patients of Malignant Tumor, Duan & Wang, Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002; 22 (7): 515-517. Effect of Astragalus Polysaccharides in Promoting Neutrophil-Vascular Endothelial Cell Adhesion and Expression of Related Adhesive Molecules, Hao, Qiu & Wu, Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004; 24 (5): 427-430. The Radioprotective Effects of Bu-Zhong-Yi-Qi-Tang: A Prescription of Traditional Chinese Medicine Astragalus, Kim, Lee, Oh, et al.  J. Chin. Med. 2002; 30 (1): 127-137. A Study on the Immune Receptors for Polysaccharides from the Roots of Astragalus membranaceus, a Chinese Medicinal Herb, Shao, Xu, Dai, et al. Biochem. Biophys. Res. Commun. 2004; 320 (4): 1103-1111. Chinese Medical Herbs for Chemotherapy Side-effects on Colorectal Cancer Patients, Taixiang, Munro & Guanjian, Cochrane Database Syst. Rev. 2005; (1): CD004540. Cohort Study on the Effect of  a Combined Treatment of Traditional Chinese Medicine and Western Medicine on the Relapse and Metastasis of 222 Patients with Stage II and III Colorectal Cancer After Radical Operation,  Yang, Ge, Wu, et al., Chin. J. Integr. Med. 2008; 144: 251-256. Clinical Observation on Treatment of Colonic Cancer with Combined Treatment of Chemotherapy and Chinese Herbal Medicine, Zhou, Shan & You, Chin. J. Integr. Med. 2009; 152: 107-111. Immune System Effects of Echinacea, Ginseng and Astragalus: A Review, Block & Mead,  Integr. Cancer Ther. 2003; 2 (3): 247-267. Chinese Medicinal Herbs Reverse Macrophage Suppression Induced by Urological Tumors, Rittenhouse, Lui & Lau,  J. Urol. 1991; 146 (2): 486-490. Integrating Chinese & Conventional Medicine in Colorectal Cancer Treatment, Lahans, Integr. Cancer Ther.  2007; 6 (1): 89-94. Chinese Herbal Medicine and Chemotherapy in the Treatment of Hepatocellular Carcinoma: A Meta-analysis of Randomized Controlled Trials, Shu, McCulloch, Xiao, et al., Integr. Cancer Ther. 2005; 4 (3): 219-229. Traditional  Chinese Medicine Herbal Treatment May Have a Relevant Impact on the Prognosis of Patients with Stage IV Adenocarcinoma of the Lung Treated with Platinum-Based  Chemotherapy or Combined Targeted Therapy and Chemotherapy, Guo, Liu, Xu, et al., Integr. Cancer Ther.  2011; 10 (2): 127-137. “And What Other Medications Are You Taking?” , Gordan, Chay, Kelly, et al., J. Clin. Oncol. 2011: 29 (11): 288-291.  {Reishi for primary liver HCC} Chinese Herbal Medicine for Cancer Pain, Xu, Lao, Ge, et al., Integr. Cancer Ther. 2007; 6 (3): 208-234. Cancer Chemo-preventative and Therapeutic Activities of Red Ginseng, Xiaoguang, Hongyan, Xiaohong, et al., J. Ethnopharmacol.  1998; 60 (1): 71-78. Current Evaluation of the Millennium Phytomedicine- Ginseng (II): Collected Chemical Entities, Modern Pharmacology, and Clinical Applications Emanated from Traditional Chinese Medicine, Jia, Zhao & Liang, Curr. Med. Chem. 2009; 16 (22): 2924-2942. Sensitization of a Tumor, But Not Normal Tissue, to the Cytotoxic Effect of Ionizing Radiation Using Panax Notoginseng  Extract, Chen ,Wu,  Wang , et al., Am. J. Chin. Med. 2001; 29 (3-4): 517-524. Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent, Fried & Arbiser, Antioxid. Redox Signal. 2009; 11 (5): 1139–1148. The Effects of P6 Acupressure in the Prophylaxis of Chemotherapy-Related Nausea and Vomiting in Breast Cancer Patients, Molassiotis, Helin, Dabbour, et al., Complement. Ther. Med. 2007; 15 (1): 3-12. Acupuncture: Role in Comprehensive Cancer Care – A Primer for the Oncologist and Review of the Literature, Cohen, Menter & Hale, Integr. Cancer Ther. 2005; 4 (2): 131-143. Acupuncture as Palliative Therapy for Physical Symptoms and Quality of Life for Advanced Cancer Patients, Dean-Clower, Doherty-Gilman, Keshaviah, et al., Integr. Cancer Ther. 2010; 9 (2): 158-167. The Management of Cancer Related Fatigue After Chemotherapy with Acupuncture and Acupressure: A Randomized Controlled Trial, Molassiotis, Sylt & Diggins,  Complement. Ther. Med.  2007; 154: 228-237. Acupuncture to Alleviate Chemotherapy-induced Nausea and Vomiting in Paediatric Oncology – A Randomized Multicenter Cossover Pilot Trial, Gottschling, Reindl, Meyer, et al., Klin. Paediatr. 2008; 220 (6): 365-370. Acupuncture for the Treatment of Vasomotor Symptoms in Breast Cancer Patients Receiving Hormone Suppression Treatment, Walker, et al., Int. J. Rad. Oncol. – Biol. – Phys.  2008; Abstract No. 228. Volume 72, Number 1. Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea or Vomiting, Ezzo, Richardson,Vickers, et al., Cochrane Database Syst. Rev. 2006; 2: CD002285.  DOI:10.1002/14651858. CD002285.pub2. Cochrane Review Summary for Cancer Nursing: Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea or Vomiting, Konno, Cancer Nurs. 2010; 33 (6): 479-480. Acupuncture Versus Venlafaxine for the Management of Vasomotor Symptoms in Patients with Hormone Receptor-Positive Breast Cancer: A Randomized Controlled Trial, Walker, Rodrigues, Kohn, et al., J. Clin. Oncol. 2009; Epub ahead of print PMID: 20038728. Acupuncture in the Rehabilitation of Women After Breast Cancer Surgery- A Case Series, Alem & Gurgel,  Acup. Med. 2008; 262: 86-93. Monitoring of Neuromuscular Blockade at the P6 Acupuncture Point Reduces the Incidence of  Post-operative Nausea and Vomiting, Arnberger, Stadelmann, Alischer, et al., Anesthesiology 2007; 107 (6): 903-908.  Clinical Observations on Post-operative Vomiting Treated by Auricular Acupuncture,  Kim, Kim & Kim, Am. J. Chin. Med. 2003; 31 (3): 475-480. Clinical Uses of P6 Acupuncture Anti-emesis, Dundee & McMillan, Acup.  Electrother. Res. 1990; 15 (3-4): 211-215. Acupuncture for Nausea and Vomiting: An Update of Clinical and Experimental Studies,  Streitberger, Ezzo & Schneider, Auton. Neurosci. 2006; 129( 1-2): 107-117. Effect of Acupressure on Nausea and Vomiting Induced by Chemotherapy in Cancer Patients, Gardani, Cerrone, Biella, et al.,  Minerva Med. 2006; 97 (5): 391-394. Electroacupuncture for Refractory Acute Emesis Caused by Chemotherapy, Choo, Kong, Lim, et al.,  J. Altern. Complement. Med. 2006; 12 (10): 963-969. Acupuncture-point Stimulation for Chemotherapy-Induced Nausea or Vomiting, Ezzo, Richardson, Vickers, et al., Cochrane Database Syst. Rev. 2006; (2): CD002285. Effects of Electro-acupuncture on T-cell Subpopulations, NK Activity, Humoral Immunity and Leukocyte Count in Patients Undergoing Chemotherapy, Ye, Liu, Wang & Xu,  J. Trad. Chin. Med. 2007; 271: 19-21. Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients, a Randomized, Controlled Trial, Hervik  & Mjaland, Breast Cancer Res. Treat. 2009; 1162: 311-316. Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea or Vomiting,  Ezzo, Richardson, Vickers, et al., Cochrane Database of Systematic Reviews  2006; 2: CD002285. Acupuncture for Dysphagia After Chemo-radiation Therapy in Head and Neck Cancer: A Case Series Report, Lu, Posner, Wayne, et al., Integr. Cancer Ther. 2010; 9 (3): 284-290. Acupuncture versus Metoclopramide in the Treatment of Postoperative Gastroparesis Syndrome in Abdominal Surgical Patients: A Randomized Controlled Trial, Sun, Luo, Wu, et al., J. Chin. Integr. Med. 2010; 8 (7): 641.

CO-ENZYME Q10 Coenzyme Q10 Plasma Levels Predict Melanoma Metastasis, Rusciani, et al,  J. Am. Acad. Dermatology, 2006; 54: 234-241.   Coenzyme Q Differentially Modulates Phospholipid Hydroperoxide Glutathione Peroxidase Gene Expression and Free Radicals Production in Malignant and Non-malignant Prostate Cells, Quiles, Farquharson, Ramirez-Tortosa, et al., Biofactors 2003; 18 (1-4): 265-270. Clinical Response of Myelodysplastic Syndromes Patients to Treatment with Coenzyme Q10, Galili, Sechman, Cerny, et al., Leuk Res. 2007 J; 31 (1): 19-26. Coenzyme q10 for Prevention of Anthracycline-induced Cardiotoxicity, Conklin, Integr Cancer Ther. 2005; 4 (2): 110-130. CoQ10:  Could It Have a Role in Cancer Management?, Hodges, Hertz, Lockwood & Lister,  BioFactors 1999; 9: 365-370. An Analysis of the Role of Coenzyme Q in Free Radical Generation and As an Antioxidant, Beyer, Biochem. & Cell Biol.1992; 70 (6): 390-403. The Mode of Action of Lipid-soluble Antioxidants in Biological Membranes. Relationship Between the Effects of Ubiquinol and Vitamin E as Inhibitors of Lipid Peroxidation in Submitochondrial Particles, Ernster, Forsmark  & Nordenbrand,  J. Nutr. Sci. & Vitamin. 1992; Spec No: 548-551. Improved Survival in Patients with End-Stage Cancer Treated with Coenzyme Q10 and Other Antioxidants, Hertx & Lister, J. Int. Med. Res. 2009; 37: 1961-1971.

CURCUMIN & INFLAMMATION Curcumin and Green Tea Polyphenols: Synergistic Anticancer Compounds, Yarnell, Quart. Rev. Nat. Med. 1998; Fall: 218-220. Antioxidant and Anti-inflammatory Properties of Curcumin, Menon & Sudheer, Adv. Exp. Med. Biol. 2007; 595: 105-125. Curcumin and Resveratrol Inhibit Nuclear Factor-kappaB-mediated Cytokine Expression in Adipocytes, Gonzales & Orlando, Nutr. Metab. (Lond). 2008; 5 (1): 17. Regulation of COX and LOX by Curcumin, Rao, Adv. Exp. Med. Biol. 2007; 595: 213-226. Induction of Apoptosis by Curcumin and its Implications for Cancer Therapy, Karunagaran, Rashmi  & Kumar, Curr. Cancer Drug Targets 2005; 5 (2): 117-129.  Biological Effects of Curcumin and its Role in Cancer Chemoprevention and Therapy, Singh & Khar, Anticancer Agents Med.Chem. 2006; 6 (3): 259-270. Chemotherapeutic Potential of Curcumin for Colorectal Cancer, Chauhan, Curr. Pharm. Des. 2002; 8 (19): 1695-1706. Curcumin Dually Inhibits Both mTOR and NF-{kappa}B Pathways Through a Crossed PI3K/Akt/IKK Signaling Axis in Adenoid Cystic Carcinoma, Sun, Chen, Zhang, et al., Mol. Pharmacol. 2010; [Epub ahead of print] PMID: 20959361. Synergistic Inhibitory Effects of Curcumin and 5-FluoroUracil on the Growth of the Human Colon Cancer Cell Line HT-29,  Du, Jiang, Xia & Zhong, Chemotherapy 2006;52 (1): 23-28. Curcumin Inhibits Human Colon Cancer cell Growth by Suppressing Gene Expression of Epidermal Growth Factor Receptor Through Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu & Johnson, Oncogene 2005; Sept. 19, Epub. Molecular Targets of Curcumin, Lin, Adv. Exp. Med. Biol. 2007; 595: 227-243. Curcumin, an Anti-oxidant and Anti-tumor Promoter, Induces Apoptosis in Human Leukemia Cells, Kuo, Huang & Lin,  Biochem Biophys Acta 1996; 131 (7): 95-100. The Chemopreventive Agent Curcumin is a Potent Radiosensitizer of Human Cervical Tumor Cells via Increased Reactive Oxygen Species Production and Overactivation of the Mitogen-activated Protein Kinase Pathway, Javvadi, Segan, Tuttle & Koumenis,  Mol Pharmacol. 2008 May; 73 (5): 1491-501. Curcumin, a Dietary Component, has Anti-cancer, Chemo-sensitization, and Radio-sensitization Effects by Down-regulating the MDM2 Oncogene Through the P13K/mTOR/ETS2 Pathway, Zhang, Hill, Wang & Zhang, Cancer Res. 2007; 67 (5): 1988-1996. Cellular Foundation of Curcumin-induced Apoptosis in Follicular Lymphoma Cell Lines, Skommer, Wlodkowic & Pelkonen, Exp. Hematol. 2006; 34 (4): 463-474. Curcumin Inhibits Human Colon Cancer Cell Growth by Suppressing Gene Expression of Epidermal Growth Factor Receptor Through Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu  & Johnson, Oncogene 2006; 25: 278-287. Therapeutic Potential of Curcumin in Human Prostate Cancer-1.  Curcumin Induces Apoptosis in Both Androgen-dependent and Androgen-independent Prostate Cancer Cells,  Dorai, Gehani & Katz,  Prost. Cancer Prost. Dis.  2000; 3: 84-93. Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer, Somasundaram, Edmund, Moore, et al., Cancer Res.   2002; 62 (13): 3868-3875. Can a Common Spice be Used to Treat Cancer?, Witter, Oncolog.  2007; 52 (9): 4-5. Curcumin and Colorectal Cancer: Add Spice to Your Life, Kunnumakarra, Guha &Aggarwal, Curr. Colorect. Cancer Rep. 2009; 5: 5-14. Curcumin as Chemosensitizer, Limtrakul, Adv. Exp. Med. Biol. 2007; 595: 269-300. Chemopreventive and Therapeutic Effects of Curcumin [Mini-Review],Duvoix, Blasius, Delhalle, et al., Cancer Letters 2005; 223: 181–190. Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer, Somasundaram, Edmund, Moore, et al., Cancer Res. 2002; 62 (13): 3868-3875. Modulation of Function of Three Drug Transporters, P-Glycoprotein (ABCB1), Mitoxantrone Resistance Protein (ABCG2) and Multi-drug Resistance Protein 1 (ABCC1) by Tetrahydrocurcumin, a Major Metabolite of Curcumin, Limtrakul, Chearwae, Shukia, et al., Mol. Cell  Biochem. 2007; 296 (1-2): 85-95. Aspirin, COX-2 Inhibitors Effective as Adjuvant Therapy in Stage III Colon Cancer, Fuchs, Amer. Soc. Clin. Onc., AGM  May 16, 2005; Abstract 3530, as reported by Schuster, Medscape Medical News, May 2005; article 504976. Helicobacter Infection, Chronic Inflammation and the Development of Malignancy, Crowe, Curr. Opin. Gastroenterol. 2005; 21 (1): 32-38. Nutritional and Botanical Modulation of the Inflammatory Cascade – Eicosanoids, Cyclooxygenases and Lipoxygenases – As an Adjunct in Cancer Therapy,  Wallace, Integr. Cancer Ther. 2002; 1 (1): 7-37. Inflammation, COX-2 Inhibitors, & Cancer, Block, Integr. Cancer Ther. 2005; 4 (1): 3-4. Inflammation and Cancer: An Ancient Link with Novel Potentials, Perwez Hussain & Harris,  Int. J. Cancer  2007; 121 (11): 2373-2380. NF-kappaB: A Stress-regulated Switch for Cell Survival, Piva, Belardo & Santoro,  Antioxid. Redox  Signal. 2006; 8 (3-4): 478-486. Cancer Cachexia and Targeting Chronic Inflammation: A Unified Approach to Cancer Treatment and Palliative/Supportive Care, MacDonald,  J. Support. Oncol. 2007; 5 (4): 157-162. Inflammation and Cancer, Coussens & Werb, Nature 2002; 420 (6917): 860-867. Significance and Relationship Between Infiltrating Inflammatory Cell and Tumor Angiogenesis in Hepatocellular Carcinoma Tissues, Peng, Deng, Yang, et al.,  World J Gastroenterol. 2005; 11 (41): 6521-6524. Inflammatory Cell Infiltration of Tumors: Jekyll or Hyde, Talmadge, Donkor, & Scholar,  Cancer Metastasis Rev. 2007; 26 (3-4): 373- 400. Bioavailability of Curcumin: Problems and Promises, Anaand, Kunnumakkara, Newman, et al., Molec. Pharm. 2007; 4 (6): 807-818. Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer, Dhillon, Aggarwal, Newman, et al., Clin. Cancer Res. 2008; 14 (14): 4491-4499.  Inflammation and Prostate Cancer, Vasto, Carruba, Candore, et al., Future Oncol. 2008; 4 (5): 637-645. Prevention and Treatment of Pancreatic Cancer by Curcumin in Combination with Omega-3 Fatty Acids, Swamy, Citineni, et al, Nutr. Cancer  2008; 60 Suppl. 1: 81-89. Curcumin Inhibits Human Colon Cancer Cell Growth by Suppressing Gene Expression of Epidermal Growth Factor Receptor Through Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu & Johnson, Oncogene 2006; 25 (2): 278-287. Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer, Dhillon, Aggarwal, Newman, et al., Clin. Cancer Res. 2008; 14 (14): 4491-4499. Inhibitory Effect of Curcumin, a Food Spice from Turmeric, on Platelet-activating Factor and Arachidonic Acid-mediated Platelet Aggregation Through Inhibition of Thromboxane Formation and Ca2+ Signalling, Shah, Nawaz, Pertani, et al., Biochem. Pharmacol. 1999; 58 (7): 1167-1172. Combination Treatment with Curcumin and Quercetin of Adenomas in Familial Adenomatous Polyposis, Cruz-Correa, Shoskes, Sanchez, et al., Clin. Gastroenterol. Hepatol. 2006; 4 (8): 1035-1038. Curcumin Inhibits Proliferation, Invasion, Angiogenesis and Metastasis of Different Cancers Through Interaction with Multiple Cell Signaling Proteins, Kunnumakkara, Anand &Aggarwal, Cancer Lett. 2008;[Epub ahead of print]. Curcumin (Diferuloylmethane) Down-regulates Expression of Cell Proliferation and Anti-apoptotic and Metastatic Gene Products Through Suppression of I-kappaB-alpha Kinase and Akt Activation, Aggarwal, Ichikawa, Takada, et al., Mol. Pharmacol. 2006; 69 (1): 195-206. Curcumin Down-Regulates the Multidrug-resistance Mdr1b Gene by Inhibiting the PI3K/Akt/NF kappa B Pathway, Choi, Kim, Lim, et al., Cancer Lett. 2008; 259 (1): 111-118. Amelioration of Immune Cell number Depletion and Potentiation of Depressed Detoxification System of Tumor-bearing Mice by Curcumin, Pal, Bhattacharyya, Choudhuri, et al., Cancer Detect. Prev. 2005; 29 (5): 470-478 Vitamin Antioxidants, Lipid Peroxidation, Tumour Stage, the Systemic Inflammatory Response and Survival in Patients with Colorectal Cancer, Leung, Crozier, Talwar, et al., Int. J. Cancer  2008; 12310: 2460-2464. Evaluation of Anti-inflammatory Property of Curcumin (diferuloyl methane) in Patients with Postoperative Inflammation, Satoskar, Shah & Shenoy,   Int. J. Clin. Pharmacol. Ther. Toxicol. 1986; 24: 651-654. Biological Effects of Curcumin and its Role in Cancer Chemoprevention and Therapy, Singh & Khar,  Anticancer Agents Med. Chem. 2006; 6 (3): 259-270. Chemotherapeutic Potential of Curcumin for Colorectal Cancer, Chauhan, Curr. Pharm. Des. 2002; 8 (19): 1695-1706 Suppression of the Nuclear Factor-kappaB Activation Pathway by Spice-derived Phytochemicals: Reasoning for Seasoning, Aggarwal & Shishodia, Ann. N. Y. Acad. Sci. 2004; 1030: 434-441. Phase I Dose Escalation Trial of Docetaxol Plus Curcumin in Patients with Advanced and Metastatic Breast Cancer, Bayet-Robert, Kwiatkowski, Leheurteur, et al., Cancer Biol. Ther. 2010, 9 (1): [Epub ahead of print}. PMID 19901561. Curcumin in Combination with Bortezomib Synergistically Induced Apoptosis in Human Multiple Myeloma U266 Cells, Park, Ayyappan, Bae, et al., Molecular Oncology 2009 2 (4): 317-326. Curcumin Circumvents Chemoresistance in vitro and Potentiates the Effect of Thalidomide and Bortezomib Against Human Multiple Myeloma in Nude Mice Model, Sung, Kunnumakkara, Sethi, et al., Mol. Cancer Ther. 2009; 8 (4): 959-970. Curcumin as an Anti-cancer Agent: Review of the Gap Between Basic and Clinical Applications, Bar-Sela, Epelbaum & Schaffer, Curr. Med. Chem. 2010; 17 (3): 190-197(8). Aromatase Inhibitor Letrozole in Synergy with Curcumin in the Inhibition of Xenografted Endometrial Carcinoma Growth, Liang, Hao, Wu, et al., Int. J. Gynecol. Cancer 2009; 19 (7): 1248-1252. Curcumin Inhibits Prosurvival Pathways in Chronic Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in Combination with EGCG, Ghosh, Kay, Secreto & Shanafelt, Clin. Cancer Res. 2009; 15 (4): 1250-1258. Elimination of Colon Cancer Stem-like Cells by the Combination of Curcumin and FOLFOX, Yu, Kanwar, Patel, et al., Transl. Oncol. 2009; 2 (4): 321-328. Curcuma wenyujin Extract Induces Apoptosis and Inhibits Proliferation of Human Cervical Cancer Cells in Vitro and in Vivo, Lim, Ky, Ng, et al., Integr. Cancer Ther. 2010; 9 (1): 36-49. Phase I/II Study of Gemcitabine-based Chemotherapy Plus Curcumin for Patients with Gemcitabine-resistant Pancreatic Cancer, Kanai, Yoshimura, Asada, et al., Cancer Chemother. Pharmacol.  2010;  published online Sept. 22, 2010:  DOI 10.1007/s00280-010-1470-2A. Comparison of Systemic Availability of Curcumin with that of Curcumin Formulated with Phosphatidylcholine, Marczylo, Verschoyle, Cooke, et al., Cancer Chemother. Pharmacol.  2007; 60 (2):171-177. Curcumin Inhibits GPVI-Mediated Platelet Activation by Interfering with the Kinase activity of Syk and the Subsequent Activation of PLCgamma2, Mayanglambam, Dangelmaier, Thomas, et al., Platelets 2010; 21 (3): 211-220. Curcumin Dually Inhibits Both mTOR and NF-{kappa}B Pathways Through a Crossed PI3K/Akt/IKK Signaling Axis in Adenoid Cystic Carcinoma, Sun, Chen, Zhang, et al., Mol. Pharmacol. 2010; [Epub ahead of print] PMID: 20959361. Curcumin: A Novel Nutritionally Derived Ligand of the Vitamin D Receptor with Implications for Colon Cancer Chemoprevention, Bartika, Whitfielda, Kaczmarskaa, et al., J. Nutr. Biochem. 2010; 21: 1153–1161. Novel STAT3 Phosphorylation Inhibitors [from Curcumin ]Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells, Lin, Hutzen, Zuo, et al., Cancer Res. 2010; 70 (6): 2445-2454. Protective Effect of Curcumin in Cisplatin-Induced Oxidative Injury in Rat Testis: Mitogen-Activated Protein Kinase and Nuclear Factor-kappa B Signaling Pathways,  Ilbey, Ozbek, Cekmen, et al., Human Reproduction 2009; 24 (7): 1717–1725. Curcumin Inhibits Pro-survival Pathways in Chronic Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in Combination with EGCG, Ghosh, Kay, Secreto & Shanafelt, Clin. Cancer Res. 2009; 15 (4): 1250-1258. Curcumin Induces Downregulation of E2F4 Expression and Apoptotic Cell Death in HCT1116 Human Colon Cancr Cells: Involvement of Reactive Oxygen Species, Kim & Lee, Korean J. Physiol. Pharmacol. 2010; 14 (6): 391-397. Curcumin in Cancer Chemoprevention: Molecular Targets, Pharmacokinetics,Bioavailability, and Clinical Trials, Shehzad, Wahid & Lee, Arch. Pharm. (Weinheim). 2010; 343 (9): 489-499. Pharmacokinetics and Pharmacodynamics of  Curcumin. Sharma, Steward & Gescher, Adv. Exp. Med. Biol. 2007; 595: 453-470. Curcumin Suppresses Human Papillomavirus Oncoproteins, Restores p53, Rb, and PTPN13 Proteins and Inhibits Benzo[a]pyrene-induced Upregulation of HPV E7, Maher, Bell, O'Donnell, et al., Mol. Carcinog. 2011; 50 (1): 47-57.    Curcumin Counteracts the Proliferative Effect of Estradiol and Induces Apoptosis in Cervical Cancer Cells, Singh & Singh, Mol. Cell Biochem. 2011; 347 (1-2):1-11. Molecular Mechanism of Curcumin Induced Cytotoxicity in Human Cervical Carcinoma Cells, Singh & Singh, Mol. Cell Biochem. 2009; 325 (1-2):107-119. Upregulation of p53 Expression in Patients with Colorectal Cancer by Administration of Curcumin, He, Shi, Wen, et al., Cancer Inv. 2011; 29: 208–213. Regression of Follicular Lymphoma with Devil’s Claw: Coincidence or Causation?, Wilson, Curr. Oncol. 2009; 16 (4): 67-70.